In comparing real-world costs and benefits of fibromyalgia medications, a clear winner emerges

In a recent study published in JAMA Network Open, researchers compared amitriptyline, an off-label medication that has not been specifically approved by the US FDA for treating fibromyalgia but is often prescribed for it, with three newer medications that are FDA-approved for this condition: pregabalin, duloxetine, and milnacipran..

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