A repurposed drug may offer relief to people with hand osteoarthritis

Osteoarthritis is a leading cause of disability worldwide — a debilitating disease that limits movement and causes pain in the joints of the knees, hips, and hands. New research has proposed mechanoinflammation as the primary driver of hand osteoarthritis and identified the importance of retinoic acid in its development. The research team showed the drug talarozole boosts the levels of retinoic acid in the joint, suppressing mechanoinflammation.

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